Organochlorine and anticholinergic pesticides in wild mice from wetland ecosystems of the Gulf of Mexico

Tammy Esperanza Chi-Coyoc, Griselda Escalona Segura, Adriana Vallarino Moncada, Jorge A. Vargas Contreras, Guillermo E. Castillo Vela, Joel Lara Reyna

Resumen


Terminos Lagoon area is a highly important economic and biological area, and one of the most important fresh water reservoirs in Mesoamerica. This area has been affected by human activities such as the disposal of pollutants, including pesticides that cause damage among wildlife. Our research evaluated the exposition of three wild rodent species Oryzomys couesi, Peromyscus leucopus, and Reithrodontomys gracilis to organochlorine and anticholinergic pesticides in nine localities of Terminos Lagoon.  We collected samples of brain, skeletal muscle, and liver to evaluate organochlorine and anticholinergic pesticides exposure. We measure acetylcholinesterase (AChE) activity as anticholinergic pesticide exposure sign.  We found significant differences in acetylcholinesterase activity among localities in brain for two species O. couesi and R. gracilis, but not for skeletal muscle tissue. We found 20 organochlorine compounds in rodent´s liver of which only lindane, aldrine and heptachlor were in amounts suggesting a recent exposure.  The AChE inhibition is not enough evidence for anticholinergic pesticide exposure. Recent organochlorine pesticides application and exposition was detected, but sources are unknown, probably atmospheric deposition.  Rodent exposure to pesticides could affect negatively its population dynamic. This detrimental effects can reach higher trophic levels because predators biomagnifies some of these compounds.


Palabras clave


Aldrin; AChE inhibition; carbamates; DDT; organophosphorus; Pollution; wild rodents

Texto completo:

PDF (English) HTML (English)

Referencias


ALBERT, L. A., AND R. LOERA. 2005. Química y Ecotoxicología de los Insecticidas. Pp 178–179, in Golfo de México Contaminación e Impacto Ambiental: Diagnóstico y Tendencias, segunda edición. (Botello A V, J. Rendón-von Osten, G. Gold-Bouchot, and C. Agraz eds.). Universidad Autónoma de Campeche, Universidad Nacional Autónoma de México, Instituto de Ecología. Campeche, México.

ALLON, N. L. RAVEH, E. GILAT, E. COHEN, J. CRUNWALD, AND Y. ASHANI. 1998. Prophylaxis against Soman Inhalation Toxicity in Guinea Pigs by Pretreatment Alone with Human Serum Butyrylcholinesterase. Toxicological Sciences 43:121-128.

ÁLVAREZ-CASTAÑEDA, S. T., T. ÁLVAREZ, AND N. GONZÁLEZ-RUIZ. 2015. Guía para la identificación de los mamíferos de México en campo y laboratorio, primera edición. Centro de Investigaciones Biológicas del Noroeste, S. C. Asociación Mexicana de Mastozoología A. C., México.

ALVES-AMARAL, G., M. PIRES-OLIVEIRA, A. L. ANDRADE-LOPES, T. CHIAVEGATTI, AND R. OLIVEIRA GODINHO. 2010. Gender-related differences in circadian rhythm of rat plasma acetyl- and butyrylcholinesterase: Effects of sex hormone withdrawal. Chemico-Biological Interactions 186:9–15.

ANDRADE-HERRERA, M. 2011. Evaluación del efecto de la contaminación atmosférica en dos especies del género Peromyscus (Rodentia: Muridae) que cohabitan en el Parque Nacional Desierto de los Leones. Universidad Autónoma Metropolitana. Unidad Iztapalapa

ASTROFF, A. B., AND A. D. YOUNG. 1998. The relationship between maternal and foetal effects following maternal organophosphate exposure during gestation in the rat. Toxicology and Industrial Health 14:869–89.

ATSDR. 2002a. Toxicological profile for DDT, DDT, DDE, and DDD. 403.

ATSDR. 2002b. Toxicological profile for aldrin/dieldrin. 303.

ATSDR. 2005. Toxicological profile for alfa-, beta-, gamma- y delta-hexachlorocyclohexane. 325.

ATSDR. 2007. Toxicological Profile for Heptachlor and Heptachlor Epoxide. 158.

BLOCK E, T. LACHER, AND R. KENDALL. 1993. Effect of the organophosphate pesticide Encounter in laboratory deer mice Peromyscus maniculatus. Environmental Toxicology and Chemistry 12:377–383.

BLOCK E. K., T. E. LACHER, L. W. BREWER, G. P. COBB, AND R. J. KENDALL. 1999. Population Responses of Peromyscus Resident in Iowa Cornfields Treated with the Organophosphorus Pesticide COUNTER. Ecotoxicology 8:189–200.

BOTELLO, A.V., J. L. ROJAS-GALAVIZ, J. BENÍTEZ, AND D. ZÁRATE-LOMELÍ. 1998. Golfo de México, Contaminación e Impacto Ambiental: Diagnóstico y Tendencias. Programa Sectorial De Medio Ambiente 1998-2005. Gobierno del Estado de Campeche. Secretaria de Ecología. Universidad Autónoma de Campeche, Epomex Serie Científica 5. Campeche, México.

BOUCHARD, M., G. CARRIER, R. C. BRUNET, P. DUMAS, AND N. NOISEL. 2006. Biological monitoring of exposure to organophosphorus insecticides in a group of horticultural greenhouse workers. The Annals of Occupational Hygiene 50:505–515

BOURGEON, S., E. H. K. LEAT, R. W. FURNESS, K. BORGA, S. A. HANSEN, AND J. O. BUSTNES. 2013. Dietary versus maternal sources of organochlorines in top predator seabird chicks: an experimental approach. Environmental Science and Technology 47:5963–70.

BRADFORD, M. M. 1976. A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Analitical Biochemistry 72:248–254.

CAMPOY, F. J., J. CABEZAS-HERRERA, AND C. J. VIDAL. 1992. Interaction of acetylcholinesterase with Lens culinaris agglutinin reveals differences in glycosylation of molecular forms in sarcoplasmic reticulum membrane subfractions. The Journal of Neuroscience 33:568–578.

CARVALHO, F. P., J. VILLENEUVE, C. CATTINI, J. RENDON, AND J. M. DE OLIVIERA. 2009. Pesticide and PCB residues in the aquatic ecosystems of Laguna de Términos, a protected area of the coast of Campeche, Mexico. Chemosphere 74:988–995.

CASTRO F., AND T. YOSHIDA. 1971. Degradation of Organochlorine Insecticides in Flooded Soils in the Philippines. Journal of Agriculture and Food Chemistry 19:1168–1170.

CHAMUCERO-SANTACOLOMA, J. C., E. TRUJILLO-TRUJILLO, AND D. A. JIMENEZ-CARVAJAL. 2011. La biodiversidad y el papel de los ingenieros de ecosistemas en su mantenimiento. Momentos de Ciencias 8:8–15.

CICOPLAFEST. 2004. Catálogo de plaguicidas. Comisión Intersecretarial para el Control del Proceso y Uso de Plaguicidas, Fertilizantes y Sustancias Tóxicas. Ciudad de México, México.

CONAGUA. 2007. Regiones Hidrológicas, escala 1:250000. República Mexicana. Ciudad de México, México.

DELL’OMO, G., M. G. PLESKACHEVA, D. P. WOLFER, H. P. LOPP, AND R. F. SHORE. 2003. Comparative effects of exposure to an organophosphate pesticide on locomotor activity of laboratory mice and five species of wild rodents. Bulletin of Environmental Contamination and Toxicology 70:138–45.

DEPLEDGE, M. H., AND M. C. FOSSI. 1994. The role of biomarkers in environmental assessment (2). Invertebrates Ecotoxicology 3:161–172

DÍAZ-GONZÁLEZ, G., A. V. BOTELLO, AND G. PONCE-VELEZ. 2005. Plaguicidas Organoclorados en Pastos y Peces de los Sistemas Candelaria-Panlau y Palizada del Este Laguna de Términos, Campeche. Pp. 207–223, in Golfo de México. Contaminación e Impacto Ambiental: Diagnóstico y Tendencias (Botello A. V., J. von Osten, G. Gold-Bouchot, and C. Agraz-Hernández, eds.). Universidad Autónoma de Campeche, Universidad Nacional Autónoma de México, Instituto Nacional de Ecología. Campeche, México.

ELLMAN, G.L., K. D. COURTNEY, V. J. ANDRES, AND R. M. FEATHERSTONE. 1961. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 7:88–95.

EPA. 1996. SW-846 Test Method 3540C: Soxhlet Extraction. Journal of Chemical Information and Modeling.

EPA. 2011. Pesticides Industry Sales and Usage. 2006 and 2007 Market Estimates. Biological and Economic Analysis Division, Office of Pesticide Programs, Office of Chemical Safety and Pollution Prevention.

FERNIE, K. J., AND R. J. LETCHER. 2010. Historical contaminants, flame retardants, and halogenated phenolic compounds in peregrine falcon (Falco peregrinus) nestlings in the Canadian Great Lakes Basin. Environmental Science and Technology 44:3520–3526.

FILDES, K., J. K. SZABO, L. ASTHEIMER, M. HOOPER, AND W. A. BUTTERMAN. 2009. Plasma cholinesterase characteristics in native australian birds: significance for monitoring avian species for pesticide exposure. Emu: Austral Ornithology 109:41–47.

FULTON, M. H., AND P. B. KEY. 2001. Acetylcholinesterase inhibition in estuarine fish and invertebrates as an indicator of organophosphorus insecticide exposure and effects. Environmental Toxicology and Chemistry 20:37–45.

GHADIRI, H., C. W. ROSE, AND D. W. CONNELL. 1995. Degradation of Organochiorine pesticides in soils under controlled environment and outdoor conditions. Journal of Environmental Management 43:141–151.

GONZÁLEZ-CASTILLO, M., C. N. AGUILAR, AND R. RODRÍGUEZ-HERRERA. 2012. Control de insectos-plaga en la agricultura utilizando hongos entomopatogenos: retos y perspectivas. Revista Científica la Universidad Autónoma de Coahuila 4:42–45.

GUPTA RK, MEACHUM S, I. HERNÁNDEZ-OCHOA, J. PERETZ, H. YAO, AND J. A. FLAWS. 2009. Methoxychlor inhibits growth of antral follicles by altering cell cycle regulators. Toxicology and Applied Pharmacology 240:1–7.

HEMINGWAY, J., AND H. RANSON. 2000. Insecticide resistance in insect vectors of human disease. Annual Review of Entomology 45:371–391.

IUCN. 2015. The IUCN Red List of Threatened Species. Version 2015-4. . Accessed 19 Nov 2015

JIMÉNEZ, B., B. MERIO, E. ABAD, J. RIVERA, AND K. OLIE. 2007. Evaluation of organochlorine compounds (PCDDs, PCDFs, PCBs and DDTs) in two raptor species inhabiting a mediterranean island in Spain. Environmental Science and Pollution Research 2:61–68.

JONES, G. Y E. C. TEELING. 2006. The evolution of echolocation in bats. Trends in Ecology and Evolution 21:149–56.

KARPUZCU, M. E., D. L. SEDLAK, AND W.T. STRINGFELLOW. 2013. Biotransformation of chlorpyrifos in riparian wetlands in agricultural watersheds: Implications for wetland management. Journal of Hazardous Material 244-245:111–120.

KLOSKOWSKI R., I. SCHEUNERT, AND W. KLEIN Y F KORTE. 1981. Laboratory screening of distribution, conversion and mineralization of chemicals in the soil-plant-system and comparison to outdoor experimental data. Chemosphere 10:1089–1100.

LARTIGES S. B., AND P. P. GARRIGUES. 1995. Degradation Kinetics of Organophosphorus and Organonitrogen Pesticides in Defferent Waters under various Environmental Conditions. Environmental Science and Technology 29:1246-1254.

LIU, B., L.L. MCCONNELL, AND A. TORRENTS. 2001. Hydrolysis of chlorpyrifos in natural waters of the Chesapeake Bay. Chemosphere 44:1315–1323.

MACKAY, D., J. P. GIESY, AND K. R. SOLOMON. 2014. Fate in the environment and long-range atmospheric transport of the organophosphorus insecticide, chlorpyrifos and its oxon. Reviews of Environmental Contamination and Toxicology 231:35-76.

MEHRANI, H. 2004. Protective effect of polyurethane immobilized human butyrylcholinesterase against parathion inhalation in rat. Environmental Toxicology and Pharmacology 16:179-185.

MITSCH, W. J., AND J. G. GOSSELINK. 2000. The value of wetlands: importance of scale and landscape setting. Ecological Economics 35:25–33

ORONA-CASTRO, F. 2008. Tecnología de producción de arroz. Inofap-SAGARPA.

PAYNE, J. R., A. MATHIEU, W. MELVIN, AND L. L. FANCEY. 1996. Acetylcholinesterase, and Old Biomarker with a New Future? Field Trails in Assosiation with Two Urban Rivers and a Paper Mill in Nowfoundland. Marine Pollution Bulletin 32:225-231.

POISSANT, L., C. BEAUVAIS, P. LAFRANCE, AND C. DEBLOIS. 2008. Pesticides in fluvial wetlands catchments under intensive agricultural activities. Science of the Total Environment 404:182–195.

QUINN, G. P., AND M. J. KEOUGH. 2007. Experimental design and data analysis for biologists, sexta edición. Cambridge University Press. Cambrige, United Kingdom.

RAMÍREZ-ELÍAS, M. A., A. V. CÓRDOVA-QUIROZ, J. G. CERÓN-BRETÓN, R. M. CERÓN-BRETÓN, J. RENDÓN-VON OSTEN, AND J. H. CORTÉS-SIMÓN. 2016. Dichloro-diphenyl-trichloroethane (DDT) and endosulfan in sediments of Sabancuy Lagoon, Campeche, Mexico. Open Journal of Ecology 6:22–31.

RATCLIFFE, D. A. 1970. Changes Attributable to Pesticides in Egg Breakage Frequency and Eggshell Thickness in Some British Birds. Journal of Applied Ecology 7:67-115.

RAVEH, L., E. GRAUER, J. GRUNWALD, E. COHEN, AND Y. ASHANI. 1997. The Stoichiometry of Protection against Soman and VX Toxicity in Monkeys Pretreated with Human Butyrylcholinesterase. Toxicology and Applied Pharmacology 145:43-53.

REID, F. 2009. A Field Guide to the Mammals of Central America and Southeast Mexico, segunda edición. Oxford University Press. Oxford, United Kindom.

REYES-MONTERO, J. A. 2014. Tecnología para la producción de mango en alta densidad de plantación. Colegio de postgraduados. Campeche, México.

ROBERTS, D. K., N. J. SILVEY, AND E. M. BAILEY. 1988. Brain Acetylcholinesterase Activity Recovery Following Acute Methyl Parathion Intoxication in Two Ferai Rodent Species: Comparison to Laboratory Rodents. Bulletin of Environmental Contaminations and Toxicology 41:26-35.

ROEGGE, C. S., O. A. TIMOFEEVA, AND F. J. SEIDLER. 2008. Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Research Bulletin 75:166–72.

SALAME MÉNDEZ, A., F. MÉNDEZ, G. AGUIRRE, AND H. SERRANO. 2008. Disrupción endocrina de la diferenciación sexual. ContactoS 70:43–49.

SAGARPA. 2014. Norma Oficial Mexicana NOM-033-SAG/ZOO-2014. Métodos para dar muerte a los animales domésticos y silvestres. Diario Oficial de la Federación, Segunda Sección. Ciudad de México, México.

SEMARNAT. 2010. Norma Oficial Mexicana NOM-059-SEMARNAT-2010. Protección ambiental– Especies nativas de México de flora y fauna silvestres – Categorías de riesgo y especificaciones para su inclusión, exclusión o cambio – Lista de especies en riesgo. Diario Oficial de la Federación, Segunda Sección. Ciudad de México, México.

SNEDEKER, S. M. 2001. Pesticides and Breast Cancer Risk: A Review of DDT, DDE, and Dieldrin. Environmental Health Perspectives 109:35-47.

SRIVASTAVA, M. K., AND R. B. RAIZADA. 2000. A limited three-generation reproduction study on hexachlorocyclohexane (HCH) in rats. Food and Chemical Toxicology 38:195-201.

SSA. 2001. Programa de Acción: Enfermedades Transmitidas por Vector. Secretaría de Salud. Ciudad de México, México.

STORY P., AND M. COX. 2001. Review of the effects of organophosphorus and carbamate insecticides on vertebrates. Are there implications for locust management in Australia? Wildlife Research 28:179 –193.

TIMOFEEVA, O. A., C. S. ROEGGE, F. J. SEIDLER, T. A. SLOTKIN Y E. D. LEVIN. 2008. Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon. Neurotoxicol Teratol 30:38–45.

TUCUCH CAUICH, F. M., A. PALACIOS PÉREZ, R. KU NAAL, AND C. GUZMÁN ESTRADA. 2005 Manejo del cultivo de mango en el estado de Campeche. 45.

VAN DER OOST. VAN DER OOST, R., J. BEYER, AND N. P. E. VERMEULEN. 2003. Fish bioaccumulation and biomarkers in environmental risk assessment : A review. Environmental Toxicology and Pharmacology 13:57–149

VILLALOBOS, G. J. 2015. Conservación y manejo del Área de Protección de Flora y Fauna “Laguna de Términos” (1994-2015). Pp. 1-20, in Aspectos socioambientales de la región de la laguna de Términos, primera edición. Campeche. Universidad Autónoma de Campeche. Campeche, México.

WALKER, K. 1999. Factors influencing the distribution of lindane and other hexachlorocyclohexanes in the environment. Enviromnental Science and Technology. 33:4373–4378.

WALKER, C. H., R. M. SIBLY, S. P. HOPKIN, AND D. B. PEAKALL. 2012. Principles of Ecotoxicology, cuarta edición, CRC Press. CIUDAD, U.S.A.

WILLIS, G. H, J. F. PARR, S. SMITH, AND B. R. CARROLL BR. 1972. Volatilization of dieldrin from fallow soil as affected by different soil water regimes. Journal of Environmental Quality 1:193–196.


Enlaces refback

  • No hay ningún enlace refback.


FACTOR DE IMPACTO 2019 (SCOPUS): 1.1


THERYA es publicada por la Asociación Mexicana de Mastozoología A. C.  Se distribuye bajo una Licencia de Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.

DERECHOS DE AUTOR Y DERECHOS CONEXOS, THERYA es una publicación digital cuatrimestral editada por la Asociación Mexicana de Mastozoología A. C.  Hacienda Vista Hermosa 107, Colonia Villa Quietud, Coyoacan 04960.  Distrito Federal, México.  Telefono (612) 123-8486, www.mastozoologiamexicana.org.  Editor responsable: Dr. Sergio Ticul Álvarez Castañeda (therya@cibnor.mx).  Reservas de Derechos al Uso Exclusivo No. 04-2009-112812171700-102, ISSN: 2007-3364 ambos otorgados por el Instituto Nacional de Derechos de Autor.  Responsable de la última actualización de este número, Unidad de informática de la Asociación Mexicana de Mastozoología A. C.  Dr. Sergio Ticul Álvarez Castañeda.  Instituto Politécnico Nacional 195.  La Paz, Baja California Sur, C. P. 23096.  Tel 612 123 8486.